.modal.modal--visible .modal-box:has(.cmp-video) a.green-button:after {
    /*position: relative;*/
    z-index: 1;
}

.modal.modal--visible button.modal__close span.modal__closeIcon:after {
    z-index: 1;
}

a.main-avatar-link:focus-visible {
    display: inline-block;
    border: 2px solid #e59700;
}
button.cmp-accordion__button:focus{
    outline: none;
}

#pioneer-homePage #runningCounter-main #runningCount-headPara a {
    background: #00707A;
}

#experts-container .cmp-masterlist__items .cmp-masterlist__item.master1:nth-child(3) {
    display: block;
}

/* Video styles starts */

.cmp-video[data-video-reference-id="phase-1b-video"] {
    position: relative;
}

.modal.modal--visible:has(.video) button.modal__close:focus,
.modal.modal--visible:has(.video) button.modal__close:focus span.modal__closeIcon:after {
    outline: none;
    border:none;
}

.cmp-video[data-video-reference-id="phase-1b-video"] .cmp-video--duration {
    display: block;
    position: absolute;
    transform: translateY(calc(-100% - 12px));
    right: 9px;
    background: white;
    font-family: 'Inter';
    color: black;
    font-weight: 500;
    font-size: 14px;
    line-height: 18px;
    max-width: 47px;
    width: 100%;
    text-align: center;
    padding: 1.5px 0;
    border-radius: 3.87px;
}

#summary-video:has(.cmp-video[data-video-reference-id="phase-1b-video"]) {
    padding-bottom: 32px;
    border-bottom: 1px solid #B6B7B9;
}

#prognostic-role-of-pten #page-content .section-3:has(#pten-charts) .footnote {
    margin-top: 15px;
}

/* Video styles ends */

#header ul.cmp-navigation__group .cmp-navigation__item--level-0:hover {
    border-bottom: 5px solid #CF6241;
}

#header ul.cmp-navigation__group .cmp-navigation__item--level-0:active {
    border-bottom: 5px solid #82290E;
}

/*compatbilty fix*/
.reference-content p a {
    color: #0A1E1A;
    pointer-events: none
}

#reference-accordion .cmp-accordion__header>button:focus-visible,
#video-library .video-cta-box a:focus-visible{
    outline: 2px solid #e59700;
}

@media screen and (max-height: 800px) and (min-width:992px) {
    #video-library .modal.modal--visible .cmp-video__player {
        height: 45vh !important;
    }

    #patholagy-images #image-container:has(#zoom-image.image-loaded) {
        height: 64vh !important;
    }
}

/* Modal dynamic height ends */


#cta-section .two-cta-section .cta.right-cta:active,
#cta-section .two-cta-section .cta.right-cta:focus {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/images/exploring-cancer-patients/unmet-needs/desktop/button-bg-right.png) !important;
}

#cta-section .two-cta-section .cta.right-cta:active:before,
#cta-section .two-cta-section .cta.right-cta:focus:before {
    display: none;
}

#cta-section .two-cta-section .cta.right-cta:before {
    content: "";
    position: absolute;
    width: 100%;
    height: 100%;
    left: 0;
    top: 0;
    border-radius: 8px;
    background: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/images/global/desktop/hover-img.png);
    z-index: 0;
    background-size: 105%;
    background-repeat: no-repeat;
    background-position: center;
    opacity: 0;
    transition: all 0.3s ease;
}

#cta-section .two-cta-section .cta.right-cta:hover:before {
    opacity: 0.85 !important;
    background-size: cover;
}

#prognostic-role-of-pten #twoCol-textComp {
    background: #E6F4F5;
    border-radius: 12px;
}

#explore-key-section .masterContentList .cmp-masterlist__item-content span.cmp-masterlist__item-cta {
    background-color: #00707A;
    width: 100%;
    border-radius: 42.3px;
    padding: 10px 0;
    max-width: 306px;
    display: flex;
    position: absolute;
    bottom: 28px;
}

#explore-key-section a.cmp-masterlist__item-cta-link {
    color: white;
    padding: 28px 28px 74px;
    display: inline-block;
    min-height: 261px;
    position: relative;
    border-radius: 14px;
}

#explore-key-section .masterContentList .cmp-masterlist__items .cmp-masterlist__item {
    padding: 0;
}

#explore-key-section .masterContentList .cmp-masterlist__items .cmp-masterlist__item-title,
#explore-key-section .masterContentList .cmp-masterlist__item-content .cmp-masterlist__item-description,
#explore-key-section .masterContentList .cmp-masterlist__item-content span.cmp-masterlist__item-cta>* {
    position: relative;
    z-index: 2;
}

#explore-key-section a.cmp-masterlist__item-cta-link:hover {
    text-decoration: none;
}

#explore-key-section a.cmp-masterlist__item-cta-link:hover:after {
    content: "";
    position: absolute;
    width: 100%;
    top: 0;
    bottom: 0;
    right: 0;
    left: 0;
    background: rgba(82, 194, 204, 0.5);
    border-radius: 14px;
    text-decoration: none;
}

#explore-key-section a.cmp-masterlist__item-cta-link:active:after {
    content: "";
    position: absolute;
    width: 100%;
    top: 0;
    bottom: 0;
    right: 0;
    left: 0;
    background: rgba(10, 30, 26, 0.8);
    border-radius: 14px;
    text-decoration: none;
}


/* New case studies section - desktop starts */

.new-section .green-bg {
    background: rgba(230, 244, 245, 1);
    padding: 40px;
    margin-top: 40px;
    border-radius: 12px;
}

.new-section .green-bg:last-child {
    margin-bottom: 64px;
}

.new-section .green-bg .flex-box {
    display: flex;
    align-items: center;
    gap: 32px;
}

.new-section .green-bg .flex-box .card-heading {
    font-size: 26px;
    line-height: 32px;
    font-family: 'Inter';
    font-weight: bold;
}

.new-section .green-bg .flex-box .img-box {
    max-width: 362px;
    width: 100%;
}

.new-section .green-bg .flex-box .card-content {
    font-size: 18px;
    line-height: 24px;
    margin: 8px 0 16px;
    font-family: 'Inter';
}

.new-section .green-bg .flex-box a.green-btn:after {
    content: "";
    display: inline-block;
    background: url("/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/images/global/download-icon.svg");
    width: 23px;
    height: 23px;
    vertical-align: middle;
    margin-left: 15px;
}

.new-section .green-bg .flex-box a.green-btn {
    background-color: #00707A;
    color: white;
    max-width: 307px;
    width: 100%;
    display: inline-block;
    text-align: center;
    font-size: 15.6px;
    line-height: 19.5px;
    font-family: 'Inter';
    border-radius: 41.3px;
    padding: 10px 0;
    font-weight: bold;
}

.new-section .green-bg .flex-box a.green-btn:hover {
    background-color: #24A7B3;
    text-decoration: none;
}

/* New case studies section - desktop ends */


#video-library-section {
    gap: 30px;
    flex-wrap: wrap;
    row-gap: 56px;
}

#video-library-section>.container.responsivegrid {
    max-width: 350px;
}

#video-library-section .video-desc .video-tag {
    background: #CCE9EB;
}

.modal.modal--visible .modal-box:has(.cmp-video) a.green-button:hover {
    background: #24A7B3;
    text-decoration: none;
}

.glossary-redesign .glossary-sub:last-child {
    border: none;
    padding-bottom: 0;
}

#homeBanr-mainContainer .pioneer-homeBanner-div a span.banner-anchArw::before {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/peach-cta-arrow.svg);
}

#cta-section .two-cta-section .cta.left-cta:before,
#cta-section .two-cta-section .cta.right-cta:after {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/peach-cta-arrow-white.svg);
}

#master-list-section .cmp-masterlist__item-cta-link {
    display: flex;
    flex-direction: column;
    position: relative;
}

#master-list-section .cmp-masterlist__item-cta-link span.cmp-masterlist__item-cta {
    font-size: 16px;
    line-height: 20px;
    width: 100%;
    background-color: #00707A;
    display: flex;
    color: white;
    align-items: center;
    flex-direction: row-reverse;
    justify-content: center;
    font-family: 'Inter';
    font-weight: 700;
    border-radius: 42.3px;
    padding: 11px 0;
    gap: 16px;
}

#master-list-section .cmp-masterlist__item-cta-link:hover {
    text-decoration: none !important;
}

#master-list-section .cmp-masterlist__item-cta-link:hover:after,
#master-list-section .cmp-masterlist__item-cta-link:active:after {
    content: "";
    position: absolute;
    top: -10px;
    bottom: -10px;
    left: -10px;
    right: -10px;
    background: #E6F4F5;
    border-radius: 14px;
    z-index: -1;
}

#master-list-section .cmp-masterlist__item-cta-link * {
    position: relative;
}

#master-list-section .cmp-masterlist .cmp-masterlist__item .cmp-masterlist__item-image {
    width: 100%;
    max-width: 350px;
    background-size: cover;
}

#master-list-section .cmp-masterlist__item-cta-link:active:after {
    background: #CCE9EB;
}

#prognostic-role-of-pten #twoCol-textComp .rowContMain-twoCol .colCont-child a {
    margin-top: 16px;
}

#summary-video.section-head,
#knowledge-check.section-head {
    visibility: hidden;
    height: 1px;
    margin: 0;
}

#knowledge-check-section {
    padding-top: 56px;
    border-top: 1px solid #B6B7B9;
    margin-top: 56px;
}

#external-resources #master-list-section .cmp-masterlist__item-cta-link:hover:after {
    display: none;
}

.video-cta-box a:has(img):after {
    content: "";
    position: absolute;
    width: 45px;
    height: 45px;
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/video-play-icon.svg);
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
    background-size: contain;
    background-repeat: no-repeat;
    background-position: center;
}

.video-cta-box a:has(img) {
    position: relative;
    display: inline-block;
}

.video-cta-box a:has(img):hover:after,
.cmp-video__video:hover span.cmp-video__playicon {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/video-play-icon-hover.svg);
}

.video-cta-box a:has(img):active:after,
.cmp-video__video:active span.cmp-video__playicon {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/video-play-icon-pressed.svg);
}

.cmp-video__playicon {
    background-image: url(/content/dam/intelligentcontent/unbranded/pioneerhub/us/en/phase-1b/images/global/desktop/video-play-icon.svg);
    background-size: contain;
    width: 85px !important;
    height: 85px !important;
}

.cmp-video:has(iframe) .cmp-video--duration {
    display: none !important;
}

.modal.modal--visible .modal-box:has(.cmp-video) a.green-button:hover:after {
    transform: translateX(5px);
}

.modal.modal--visible .modal-box:has(.cmp-video) a.green-button:after {
    transition: transform 0.3s ease;
}

#explore-key-section a.cmp-masterlist__item-cta-link:hover img.cmp-masterlist__item-cta-icon {
    transform: translateX(5px);
}

#explore-key-section a.cmp-masterlist__item-cta-link img.cmp-masterlist__item-cta-icon {
    transition: transform 0.3s ease;
}

#patholagy-images #master-list-section .cmp-masterlist__item-cta-link:hover:after,
#patholagy-images #master-list-section .cmp-masterlist__item-cta-link:active:after {
    display: none;
}

#image-container:has(#zoom-image) {
    background: #EBEFEF;
}

/* .modal.modal--visible {
    justify-content: center !important;
    padding: 50px 0 !important;
}

.modal.modal--visible .modal-box {
    max-height: 98%;
} */
#expert-bio {
    scroll-margin-top: 100px;
}

#pten-charts .pfs-chart .chart-flex>.chart.graph-animation .chart-bar:before {
    width: 52.5% !important;
}

#desktop-carousel .cmp-carousel__actions button.cmp-carousel__action.cmp-carousel__action--next span.cmp-carousel__action-icon:before {
    position: relative;
    right: 12px;
    left: unset;
}

#desktop-carousel .cmp-carousel__actions span.cmp-carousel__action-icon:before {
    position: relative;
    left: 12px;
}

/* Pointer pro styles starts */

#knowledge-check-section iframe {
    height: 600px !important;
}

/* Pointer pro styles ends */

.ax-content {
    padding: 20px 30px 40px;
}

.ax-content p:not(:last-child) {
    margin-bottom: 20px;
}

.ax-content p {
    font-size: 18px;
    line-height: 24px;
}

.ax-content p a {
    color: inherit;
}

/*Sliders Css*/

.cmp-carousel__content:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 1 of 8"]) .cmp-carousel__actions .cmp-carousel__action--previous,
.cmp-carousel__content:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 8 of 8"]) .cmp-carousel__actions .cmp-carousel__action--next,
.cmp-carousel__content:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 1 of 10"]) .cmp-carousel__actions .cmp-carousel__action--previous,
.cmp-carousel__content:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 9 of 9"]) .cmp-carousel__actions .cmp-carousel__action--next {
    visibility: hidden;
    pointer-events: none;
}

@media screen and (min-width:991px) and (max-width:1400px) {
    .glossary-redesign {
        padding-left: 40px;
        padding-right: 40px;
    }

    #banner .banner-section>.banner-content {
        width: 100%;
        padding: 0 40px;
    }
}

@media screen and (max-width: 991px) {

    #biomarker-driven-pageId #map-container {
        padding: 32px 0;
        border: 1px solid #B6B7B9;
        border-left: none;
        border-right: none;
    }

    #explore-key-section a.cmp-masterlist__item-cta-link {
        padding: 24px;
    }

    #explore-key-section .masterContentList .cmp-masterlist__item-content span.cmp-masterlist__item-cta {
        max-width: 306px;
    }

    .new-section .green-bg .flex-box {
        flex-direction: column;
        gap: 18px;
    }

    .new-section .green-bg {
        padding: 16px;
    }

    .new-section .green-bg .flex-box .card-heading {
        font-size: 22px;
        line-height: 26px;
    }

    .new-section .green-bg .flex-box .card-content {
        font-size: 16px;
        line-height: 20px;
    }

    #video-library-section>.container.responsivegrid {
        margin-bottom: 48px;
    }

    #video-library-section .video-title {
        padding-right: 10px;
        font-size: 22px;
        line-height: 28px;
    }

    .new-section .green-bg .flex-box a.green-btn {
        font-size: 13.6px;
        line-height: 20.5px;
        font-weight: 600;
    }

    #summary-video:has(.cmp-video[data-video-reference-id="phase-1b-video"]) {
        margin-top: 32px;
    }

    #video-library-section .video-desc {
        padding-right: 20px;
    }

    #knowledge-check-section {
        margin-top: -8px;
        padding-top: 32px;
    }

    .cmp-video__playicon {
        width: 46px !important;
        height: 46px !important;
        top: 50% !important;
        left: 50% !important;
        transform: translate(-50%, -50%);
        z-index: 0 !important;
    }

    #pathway-activation #knowledge-check-section {
        margin-top: 32px;
    }

    /* Pointer pro styles starts */

    #knowledge-check-section iframe {
        height: 980px !important;
    }

    /* Pointer pro styles ends */

    /* .expert-bio-section .box-1 {
        display: flex;
        flex-direction: column;
    }

    .expert-bio-section .box-1 .expert-card {
        order: 1;
    }

    .expert-bio-section .box-1 .expert-quote.mobile-only {
        order: 3;
        margin-bottom: 0 !important;
    }

    .expert-bio-section .box-1 .expert-contact {
        order: 2;
        margin-top: 16px;
    } */

    /*Sliders css*/

    #carousel-section #mobile-carousel .cmp-carousel__item[aria-label="Slide 1 of 10"] .image:last-child img {
        max-width: 303px !important;
        margin: 0 0 0 15px;
    }

    #mobile-carousel:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 1 of 10"]) {
        padding: 11px 0;
    }

    #mobile-carousel:has(.cmp-carousel__item.cmp-carousel__item--active[aria-label="Slide 1 of 10"]) .cmp-carousel__actions {
        display: none;
    }

    .cmp-carousel__item[aria-label="Slide 1 of 10"] .cmp-container .image:first-child {
        display: none;
    }
}

@media screen and (min-width: 992px) {
    #summary-video:has(.cmp-video[data-video-reference-id="phase-1b-video"]) {
        padding-bottom: 19px;
        margin-bottom: 56px;
    }

    #summary-video:has(.cmp-video[data-video-reference-id="phase-1b-video"]) h3.cmp-video__item-title {
        margin: 16px 0 14px;
    }

    .cmp-video[data-video-reference-id="phase-1b-video"] .cmp-video--duration {
        font-weight: 700;
        font-size: 17.4px;
        line-height: 23.2px;
        max-width: 71px;
        transform: translateY(calc(-100% - 17px));
        right: 11px;
        padding: 4.5px 0;
    }

    #video-library-section .video-desc .video-tag+p {
        padding-right: 20px;
    }

    #video-library-section .video-title {
        font-size: 22px;
        line-height: 28px;
        padding-right: 10px;
    }

    #twoCol-textComp .rowContMain-twoCol .colCont-child.phase-1b-update img {
        max-width: 482px;
    }

    .glossary-redesign .glo-desc {
        padding-right: 20px;
    }

    #page-content .section-head#case-studies {
        margin-top: 41px;
    }

    #homeBanr-mainContainer .pioneer-homeBanner-div .headPara-anchArea h1 {
        margin-top: 100px;
    }

    #twoCol-textComp .rowContMain-twoCol .colCont-child.phase-1b-update {
        text-align: right;
    }

    #strategy-tools-pageId #keyPubls-textComp .ihcPathMaster-colCommon a.anchBtn-comnCls-st {
        max-width: 297px;
        padding: 10px 30px;
        justify-content: center;
    }

    #strategy-tools-pageId #keyPubls-textComp .ihcPathMaster-colCommon {
        padding: 39px 40px;
    }

    #strategy-tools-pageId #keyPubls-textComp .ihcPathMaster-twoCol-rowMain h4 {
        margin-bottom: 8px;
    }

    /* Modal dynamic height starts */

    .modal.modal--visible:has(.cmp-video) {
        padding: 30px 0 30px !important;
    }

    .modal.modal--visible .modal-box:has(.cmp-video) {
        height: 90vh;
        max-height: 881px;
    }

    .modal.modal--visible .cmp-video__player {
        display: flex;
        align-items: center;
        justify-content: center;
        max-height: 595px;
        min-height: unset !important;
        height: 57vh !important;
    }

    .modal.modal--visible .cmp-video__thumbnail {
        height: 100%;
        width: auto;
        max-width: 100%;
        object-fit: contain;
    }

    .modal.modal--visible:has(#zoom-image) {
        padding: 30px 0 30px !important;
    }

    .modal.modal--visible .modal-box:has(#zoom-image) {
        height: 90vh !important;
    }

    #image-container:has(#zoom-image.image-loaded) {
        display: flex;
        align-items: center;
        justify-content: center;
        min-height: unset !important;
        height: 69vh !important;
    }

    #image-container:has(#zoom-image.image-loaded) img#zoom-image {
        height: 100%;
        width: 100%;
        max-width: 100%;
        object-fit: contain;
    }

    .ax-content {
        padding: 49px 0 50px;
    }
}

@media screen and (orientation: landscape) {
    .cmp-carousel__item[aria-label="Slide 1 of 10"] .cmp-container .image:last-child {
        display: none;
    }

    .cmp-carousel__item[aria-label="Slide 1 of 10"] .cmp-container .image:first-child {
        display: block;
    }
}

@media screen and (orientation: portrait) {

    .cmp-carousel__item[aria-label="Slide 1 of 10"] {
        display: block;
        visibility: visible;
    }

    #carousel-section #mobile-carousel:has(.cmp-carousel__item[aria-label="Slide 1 of 10"].cmp-carousel__item--active) ol.cmp-carousel__indicators {
        display: none !important;
    }
}

@media screen and (min-width:320px)and (max-width:370px) {

    #explore-key-section .masterContentList .cmp-masterlist__item-content span.cmp-masterlist__item-cta {
        max-width: 236px;
    }
}

@media screen and (min-width:400px)and (max-width:991px) {
    #glossary #banner .green-button {
        max-width: 306px;
    }

    #strategy-tools-pageId .ihcPathMaster-twoCol-rowMain .ihcPathMaster-colCommon-child:has(img) {
        text-align: center;
    }
}

@media screen and (min-width:992px) and (max-width:1300px) {
    #homeBanr-mainContainer .pioneer-homeBanner-div .headPara-anchArea h1 {
        margin-top: 50px;
    }
}